Endocrine Abstracts

Objectives: Metabolic dysfunction–associated fatty liver disease (MAFLD) is a new nomenclature for fatty liver disease (FLD). The clinical impact of the change in nomenclature on the ability to identify individuals at risk for cardiovascular disease (CVD) has not yet been elucidated. The aim of this study is to describe the cardiovascular risk and subclinical CVD of the different MAFLD subtypes.Methods: Retrospective analysis of patients who attende...

Aim: Epicardial adipose tissue (EAT) has important physiologic functions, nonetheless, excessive EAT leads to a proinflammatory state with adverse effects on the myocardium. EAT has also been associated with adverse outcomes in chronic kidney disease (CKD) patients. We think that visceral adipose tissue (VAT) and organ-specific ectopic fat plays an important role in cardiorenal dysfunction. The aim of our study is to analyse the relationship between EAT and the risk of develop...

Aim: Non-alcoholic fatty liver disease (NAFLD) and type 2 Diabetes (T2D) are common conditions that frequently co-exist. Studies have shown an increase likelihood of micro and macrovascular complications in this population, as well, as an increased risk of developing more severe forms of liver disease. The aim of this study was to identify diabetic complications in patients with both diseases and search for an association with liver stiffness assessed by Liver Elastography (LE...

Objectives and methods: The mechanism that explains the different weight response to various treatments in obese type 2 diabetes (DM2) patients, compared to those without diabetes, is still unknown. In order to establish the weight response to Roux-en-Y Gastric Bypass (RYGB), 268 patients with morbid obesity (IMC 45.4±0.4 kg/m2) were classified by OGTT as having normal glucose tolerance (Grupo A. n=107), prediabetes (Grupo B. n=96) an...

Aim: A key diagnostic step to determine the cause of hyperthyroidism is the measurement of circulating thyroid-stimulating immunoglobulin (TSI). High levels are associated with Graves’ disease (GD). A thyroid scintigraphy (TRS) is recommended when TSI is absent or its measurement unavailable, as TRS is capable of differentiating between GD (diffuse uptake) and toxic goitre (TG) (patchy uptake). Nevertheless, and while rarely necessary, histopathology remain the best metho...

Patients with non-alcoholic fatty liver disease (NAFLD) have a higher prevalence of cardiovascular disease, particularly patients with liver fibrosis. Studies have shown a relationship between epicardial fat/coronary calcium and myocardial ischemia.Aim: Quantify epicardial fat and coronary calcium assessed by computed tomography (CT) in patients with NAFLD. Additionally, determine whether patients with hepatic fibrosis quantitatively assessed by liver el...